Borylation and rearrangement reactions of azasilaanthracenes to afford B,N-doped nanographenes.

An air-stable B,N-containing dibenzobisanthene (8) was prepared in 29% yield by heating a 1,3,5-tri(azasilaanthryl)benzene (5) with BBr (180 °C). Under these conditions, the reaction does not stop after threefold SiMe/BBr exchange but proceeds further two rearrangement and two intramolecular C-H borylation steps. Some mechanistic details were unveiled by using smaller model systems and applying lower reaction temperatures.

Operationalizing the Consolidated Framework for Implementation Research to build and support the lived experience workforce in direct health service provision.

Background: The involvement of people with lived experience (LEX) workers in the development, design, and delivery of integrated health services seeks to improve service user engagement and health outcomes and reduce healthcare gaps. Yet, LEX workers report feeling undervalued and having limited influence on service delivery. There is a need for systematic improvements in how LEX workforces are engaged and supported to ensure the LEX workforce can fully contribute to integrated systems of care.

Green-Emitting Extended B,N-Doped Polycyclic Aromatic Hydrocarbon with Multiple Resonance Structure.

An air-stable B,N-PAH (; nine annulated six-membered rings) was synthesized from 1-X-2,6-di(azasilaanthryl)benzenes (X = Cl, I) via lithiation/borylation, electrophilic aromatic borylation, and Si/B exchange. The heteroatom distribution in meets the requirements for multiple resonance thermally activated delayed fluorescence (MR-TADF). Indeed, emits green light (λ = 523 nm; Φ = 85%; CHCl) with a small fwhm of 0.

Protein Compartments Modulate Fibrillar Self-Assembly.

A notable feature of complex cellular environments is protein-rich compartments that are formed via liquid-liquid phase separation. Recent studies have shown that these biomolecular condensates can play both promoting and inhibitory roles in fibrillar protein self-assembly, a process that is linked to Alzheimer's, Parkinson's, Huntington's, and various prion diseases. Yet, the exact regulatory role of these condensates in protein aggregation remains unknown.

Identifying Longer-Term Health Events and Outcomes and Health Service Use of Low Birthweight CALD Infants in Australia.

Introduction: Approximately one-third of all births in Australia each year are by culturally and linguistically diverse (CALD) women. CALD women are at an increased risk of adverse pregnancy and birth outcomes including prematurity and low birthweight. Infants born weighing less than 2500 g are susceptible to increased risk of ill health and morbidities such as cognitive defects including cerebral palsy, and neuro-motor functioning.