Anesthetic Challenges in Laparoscopic Surgery for a Child with Juvenile Dermatomyositis.

Conventional anesthetic management of juvenile dermatomyositis involves general anesthesia with endotracheal intubation using non-depolarizing muscle relaxants. Neuromuscular monitoring would be required for the titration of neuromuscular blocking drugs as these patients are more sensitive to these drugs, which leads to delayed recovery. Here we present a 14-year-old girl with juvenile dermatomyositis posted for laparoscopic appendicectomy.

Systematics and distribution of Lankascincus fallax (Peters, 1860) (Reptilia, Scincidae), an endemic litter-skink from Sri Lanka.

Lankascincus fallax is an endemic, but widespread species of skink distributed throughout Sri Lanka, including all bioclimatic zones (elevations from 0 to 1,200 m a.s.l.

Orthogonal CRISPR-Cas tools for genome editing, inhibition, and CRISPR recording in zebrafish embryos.

The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas universe continues to expand. The type II CRISPR-Cas system from Streptococcus pyogenes (SpyCas9) is the most widely used for genome editing due to its high efficiency in cells and organisms. However, concentrating on a single CRISPR-Cas system imposes limits on target selection and multiplexed genome engineering.