Optimization of the Esperanza window trap for the collection of the African onchocerciasis vector Simulium damnosum sensu lato.

A simple inexpensive trap (Esperanza window trap) was shown recently to collect significant numbers of Simulium ochraceum sensu lato, a major vector of Onchocerca volvulus in Mesoamerica. Here, we report studies optimizing this trap for the collection of Simulium damnosum s.l.

Cannabinoid type 1 receptors located on single-minded 1-expressing neurons control emotional behaviors.

This study has investigated the role of hypothalamic and amygdalar type-1 cannabinoid (CB1) receptors in the emotional and neuroendocrine responses to stress. To do so, we used the Cre/loxP system to generate conditional mutant mice lacking the CB1 gene in neurons expressing the transcription factor single-minded 1 (Sim1). This choice was dictated by former evidence for Sim1-Cre transgenic mice bearing Cre activity in all areas expressing Sim1, which chiefly includes the hypothalamus (especially the paraventricular nucleus, the supraoptic nucleus, and the posterior hypothalamus) and the mediobasal amygdala.

Dracunculiasis in Burkina Faso: results of a national survey.

National surveys using active reporting are essential steps in the global dracunculiasis eradication programme. All the known villages of Burkina Faso were visited at the end of 1990 by teams of field-workers who organized meetings with local informants in order to enquire about all cases of the emergence of Guinea worms during the past twelve months. The annual incidence for 1990 was then calculated using recent demographic data.