Publications by authors named "S K Yoshinaga"
Natural macrocyclic peptides produced by microorganisms serve as valuable resources for therapeutic compounds, including antibiotics, anticancer agents, and immune suppressive agents. Nonribosomal peptide synthetases (NRPSs) are responsible for the biosynthesis of macrocyclic peptides. NRPSs are large multimodular enzymes, and each module recognizes and incorporates one specific amino acid into the polypeptide product.
View Article and Find Full Text PDFBackground: Pyloric gland adenoma (PGA) is a distinct subtype of duodenal adenoma. PGA has been increasingly recognized as a histologically and molecularly distinct entity; however, its endoscopic features have not been precisely described. This study aims to investigate the endoscopic characteristics of duodenal PGA, including the association of their putative precursors, Brunner's gland hyperplasia (BGH), and gastric epithelial heterotopia/metaplasia (GEM/H).
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- The article investigates tritium levels in monthly rainfall in Hiroshima City for 2021, showing fluctuations between 0.16 to 0.78 Bq L-1.
- It also examines stable hydrogen and oxygen isotopes and ionic species to better understand precipitation characteristics and compares these trends with historical data from other areas in Japan.
- The findings indicate that while overall precipitation characteristics are similar to other regions, Hiroshima's tritium levels differ from expected patterns, suggesting potential influences from continental sources.
Background: Understanding the gait pattern of patients eligible for total hip arthroplasty (THA) due to hip osteoarthritis (OA) offers valuable information for improving locomotive syndrome (LS). This study aims to measure the gait patterns of THA-eligible patients using an optical motion capture system and to analyze these patterns using principal component analysis (PCA). Additionally, this study examines the relationship between THA-induced gait patterns and LS.
View Article and Find Full Text PDFBackground And Purpose: Efficacy of tumor embolization for posterior fossa meningioma is controversial due to the lack of adequate embolization for dangerous feeders. Of these, a meningohypophyseal trunk (MHT) has high therapeutic value despite the high risks associated with embolization.
Materials And Methods: To analyze the utility of preoperative MHT embolization for posterior fossa meningiomas using BCA with dual balloon protection, a single center retrospective record review was performed on eight consecutive patients who underwent preoperative tumor embolization via the MHT for posterior fossa meningiomas between 2020 and 2024.