Publications by authors named "S K R Sowmya"
Gingival Mesenchymal Stem Cells: A Periodontal Regenerative Substitute.
Tissue Eng Regen Med
November 2024
Background: Gingival mesenchymal stem cells (GMSCs) are distinctive homogenous subset of mesenchymal stem cells (MSCs), which has its development from neural ectomesenchyme along with contributions from the perifollicular mesenchyme and the dental follicle proper. GMSCs stand apart from other dental MSCs owing to their ease of accessibility and availability with incredible long culture sustainability without any tumorigenic capability, and stable telomerase activity. Their capacity to differentiate into various cell lineages and inherent therapeutic effect in chronic inflammatory diseases like colitis, rheumatoid arthritis, systemic lupus erythematous (SLE) and diabetes makes them immensely valuable.
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- Oral lichen planus (OLP) is a chronic inflammatory condition affecting the oral mucosa, which can severely impact patients' quality of life due to discomfort and anxiety.
- A study at Saveetha Dental College analyzed the anxiety and depression levels of 212 OLP patients, with their data collected over one year, including factors like age, gender, and associated medical conditions.
- The study found that the most affected age group was 51-60 years, predominantly female, with many reporting burning sensations as the main symptom, and a small percentage having comorbidities like Grinspan syndrome.
Background: By resolving the difficulties associated with missing teeth, implant-supported restorations have emerged as a key component of contemporary dentistry. The choice of prosthetic materials is crucial in establishing the durability and clinical efficacy of these restorations.
Methods: A prospective design was used at a tertiary care hospital with 150 patients receiving implant-supported restorations.
Introduction Epilepsy, a chronic neurological disorder marked by recurrent seizures, affects approximately 50 million people worldwide with a higher prevalence in developing countries. This condition challenges motor skills and coordination, leading to poor oral health maintenance. The study aimed to evaluate the effect of epilepsy on oral health outcomes in adults by contrasting South Indian epileptics with healthy controls.
View Article and Find Full Text PDFPhytic acid (inositol hexaphosphate/IP6) is a versatile chemical that is abundant in nature and is required for a variety of biological processes. It is harnessed in a wide range of fields, including drug discovery, daily supplies, chemical industries, medicine, and dentistry. IP6 is becoming increasingly popular in dentistry, with promising results.
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