Neurodevelopmental outcomes after infant heart surgery for congenital heart disease: a hospital-based multicentre prospective cohort study from India.

Background: Neurodevelopmental disability is a common long-term concern following surgery for congenital heart disease (CHD). Little information is available from low-resource environments where the majority of children with CHD are born. Several challenges in the CHD care continuum exist in such environments.

Optimizing the production and efficacy of antimicrobial bioactive compounds from in combating multi-drug-resistant pathogens.

Background: The rise of antibiotic-resistant pathogens has intensified the search for novel antimicrobial agents. This study aimed to isolate from local soil samples and evaluate its antimicrobial properties, along with optimizing the production of bioactive compounds.

Methods: Soil samples were collected from local regions, processed, and analysed for Streptomyces strains isolation using morphological characteristics and molecular identification through 16S rRNA gene PCR assay.

Efficacy of Bilastine, Dextromethorphan, and Phenylephrine Syrup in Patients With Dry Cough: A Phase 3 Randomised Trial.

Background Cough in common cold is often associated with rhinorrhoea and nasal congestion, requiring treatment with a cough suppressant, decongestant, and antihistamine. Bilastine is a non-sedating antihistamine, a preferred option over sedating antihistamines. A combination of bilastine, dextromethorphan, and phenylephrine is expected to provide non-sedating treatment for cough associated with a common cold or allergy.

Looking back into the Hepatitis C Virus epidemic dynamics from Unnao, India through phylogenetic approach.

Viral hepatitis is a major public health challenge. Hepatitis C Virus (HCV) infection causes the progressive liver damage. A surprisingly high number of individuals tested positive for HCV infection during the Unnao Human Immunodeficiency Virus (HIV) outbreak investigation in 2017-2018 (more than 90% of the people living with HIV were from the Premganj township and Chakmeerapur village of the district in the northern State of Uttar Pradesh).

Guide-wire and K-wire readjustment jig for osteotomy and osteosynthesis: An instrument.

Introduction: Numerous orthopaedic procedures including dynamic hip screw plating and various osteotomies require placement of a reference guide pin or K wire to direct bone cuts or for drilling screw holes. Appropriate positioning of these wires is a critical component of surgery. Irrespective of whether one is a seasoned surgeon or an apprentice, these wires often need repositioning and readjustment.