Vermiform appendiceal cancers are rare and commonly diagnosed incidentally after appendectomy for acute appendicitis. Establishing a diagnosis and staging appendiceal cancer is important as the treatment options differ based on the subtypes of tumor and their spread in the peritoneum. The role of endosonography in tissue diagnosis of appendiceal cancer is limited.
View Article and Find Full Text PDFProstate cancer (PC) is among the most prevalent cancers in males. It is the leading cause of death in men, in around 48 out of 185 countries. Increased androgen receptor (AR) activity is the key factor contributing to the development or progression of newly diagnosed cases of prostate cancer.
View Article and Find Full Text PDFIntroduction: The changes in histone modifications are linked to the progression of benign and normal tissue to malignancy. Thus, numerous findings suggest that targeting epigenetic factors might be a focus for anti-cancer treatment. In this study, we tested the hypothesis that telomerase activator might be a potential epigenetic regulator in combatting skin cancer cell proliferation.
View Article and Find Full Text PDFBackground And Objectives: Heart disease and diabetes are leading causes of death in the U.S., with timely screening, referrals, and education being critical for effective treatment.
View Article and Find Full Text PDFWithering is one of the major processing steps critical for the quality of black tea. In this study, we investigated the mechanisms underlying the physicochemical changes in metabolites and gene expression during the withering process of black tea using metabolomic and transcriptomic approaches, respectively. Based on gas chromatography/mass spectrometry non-targeted metabolomic approaches (GC-MS) and ultra-high performance liquid chromatograph-tandem mass spectrometry (UHPLC-MS/MS), a total of 76 volatile compounds and 160 non-volatile compounds were identified from tea leaves, respectively.
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