Publications by authors named "S K Nijjar"

Background: Caesarean scar ectopic pregnancy (CSEP) is associated with significant maternal and foetal morbidity. However, the optimal treatment remains unknown.

Objectives: The aim of this study was to review outcomes reported in studies on CSEP treatment and outcome reporting quality.

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Connexins allow intercellular communication by forming gap junction channels (GJCs) between juxtaposed cells. Connexin26 (Cx26) can be regulated directly by CO. This is proposed to be mediated through carbamylation of K125.

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Objective: To establish a normal reference interval for amniotic sac diameter (ASD) between 7 + 0 and 9 + 6 weeks' gestation and its relative size in relation to gestational sac diameter (GSD) and the embryo crown-rump length (CRL).

Methods: This was a prospective, cross-sectional study of consecutive women presenting to the Early Pregnancy Unit, University College Hospital, London, UK, between August 2022 and June 2023. We included live, normally sited, singleton pregnancies with a normal 20-week anomaly scan.

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Article Synopsis
  • The study focuses on the management of advanced Cesarean scar ectopic pregnancies (CSEPs), which pose significant risks and typically require hysterectomy, while exploring whether conservative treatments such as suction curettage and interventional radiology could be effective.* -
  • Out of 371 cases reviewed over 15 years, 22 women had advanced live CSEPs, with 17 opting for surgery; they underwent procedures that included suction curettage and placement of a cervical suture for hemostasis.* -
  • Results showed that the cervical suture effectively controlled bleeding in 76% of surgical cases, with additional measures like uterine artery embolization used when necessary, marking a significant finding in managing these complex pregnancies.*
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Objective: To determine the natural progression of ovarian endometrioma in women who are managed expectantly.

Methods: This was a retrospective cohort study of 83 women with evidence of ovarian endometrioma who were managed expectantly between April 2007 and May 2022. The study was conducted in the Department of Women's Health, University College London Hospitals and The Gynecology Ultrasound Centre, London, UK.

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