Publications by authors named "S K Napier"
Background: Recurrent respiratory papillomatosis (RRP) is a rare debilitating condition caused by chronic infection with human papillomavirus (HPV) type 6 or 11. Papillomas develop in the aerodigestive tract, leading to significant voice disturbance and airway obstruction. No systemic treatment currently exists.
View Article and Find Full Text PDFWe report a general chemoselective strategy for amide bond formation with poorly nucleophilic amines in the presence of reactive primary alcohols or amines as the competing nucleophiles. The selectivity for less reactive amines over competing alcohols was achieved using TCFH and catalytic Oxyma as a highly reactive, inexpensive, and safe reagent combination. By temporarily masking more reactive amines as imines through the use of electron-deficient aldehydes, the hindered amines could be similarly coupled with high efficiency and selectivity.
View Article and Find Full Text PDFBackground: Online child sexual victimization is increasingly facilitated by technology, but evidence of its prevalence and characteristics remains scarce. Reliable population-based data is critical to understand the magnitude and nature of the problem, and inform evidence-based prevention.
Objective: To determine the prevalence of nonconsensual sharing of sexual images of the child by any perpetrator, and of online sexual solicitation by any adult perpetrator; and to determine the characteristics of these experiences.
Article Synopsis
- - The study aims to understand the behaviors of individuals who consume child sexual abuse material (CSAM) by identifying predictors of both initial and ongoing use.
- - Key findings show that significant predictors for ever viewing CSAM include being male, older age groups (25-34 and 55+), earlier exposure to adult pornography, and experiencing childhood abuse, with nearly half of initial viewers intentionally watching CSAM again.
- - The results highlight the need for prevention strategies targeting those at risk of first exposure to CSAM, as well as interventions to address continued usage after initial exposure.