Publications by authors named "S K Mohite"
Article Synopsis
- The pyridine core is vital in many FDA-approved drugs and EPA-regulated chemicals, serving as a key structural component in various applications like ligands and catalysts.
- Direct functionalization of pyridine is challenging due to its unstable nature and nitrogen's strong coordination, but recent advancements in regioselective C-H activation techniques show promise for improving this process.
- This review highlights innovative strategies for meta and para-C-H functionalization, discussing both their advantages and limitations, to encourage further developments in pyridine chemistry.
Introduction Periodontitis is a multifactorial oral disease causing destruction of the periodontium. Systemic diseases can exacerbate periodontal inflammation through immune dysregulation. N-terminal-probrain natriuretic peptide (NT-proBNP) a prohormone, released by myocardial cells is a known biomarker for cardiovascular disease (CVD).
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- A study examined vitamin D, calcium, and parathyroid hormone (PTH) levels in 36 children with β-thalassemia compared to 36 matched controls, revealing significant deficiencies in the case group.
- Results showed that children with β-thalassemia had much lower hemoglobin and vitamin D levels, and higher serum ferritin compared to controls, indicating poor bone health risk.
- The findings suggest that the high prevalence of vitamin D deficiency and PTH deficit among thalassemic children could lead to growth failure and metabolic bone diseases.
Background and aim is an opportunistic pathogen responsible for various healthcare-related infections, which are difficult to treat due to intrinsic and acquired resistance. This study aimed to investigate AmpC β-lactamase production using phenotypic and genotypic methods in strains isolated from a tertiary care hospital in Karad, Maharashtra, India. Material and methods Over one year, a descriptive cross-sectional study was conducted at the Department of Microbiology, Krishna Institute Medical Sciences, Krishna Vishwa Vidyapeeth, Karad.
View Article and Find Full Text PDFTrehalose serves as a primary circulatory sugar in insects which is crucial in energy metabolism and stress recovery. It is hydrolyzed into two glucose molecules by trehalase. Silencing or inhibiting trehalase results in reduced fitness, developmental defects, and insect mortality.
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