Publications by authors named "S K Marani"
Article Synopsis
- - The study aimed to compare the dosimetric outcomes of intensity modulated radiotherapy (IMRT) and 3D conformal radiotherapy for patients with locally advanced supraglottic tumors after surgery and post-operative treatment.
- - Researchers created a virtual treatment plan using 3D conformal techniques for 20 patients and compared it to actual IMRT plans, focusing on 18 critical structures related to swallowing and oral functions.
- - Results indicated that IMRT significantly reduced the radiation dose to various structures, underscoring its potential benefits, but further studies are needed to validate these findings and examine their impact on patient outcomes.
Objective: Tumor-associated macrophages (TAMs) are the most represented cells of the immune system in the tumor microenvironment (TME). Besides its effects on cancer cells, radiation therapy (RT) can alter TME composition. With this systematic review, we provide a better understanding on how RT can regulate macrophage characterization, namely the M1 antitumor and the M2 protumor polarization, with the aim of describing new effective RT models and exploration of the possibility of integrating radiation with other available therapies.
View Article and Find Full Text PDFBackground: People with substance or alcohol use disorders (SUDs/AUDs) are likely to be more vulnerable to COVID-19 infection than the general population, but the evidence of COVID-19-related mortality in these patients is unclear.
Objectives: The aim of the study was to verify whether patients with AUD and SUD have a higher mortality rate for COVID-19-related mortality compared to the general population.
Method: We performed a follow-up study to assess mortality in 2020 in a cohort of patients diagnosed for the first time with AUDs or SUDs at the Public Health Services in the metropolitan area of Bologna (Northern Italy) from 2009 to 2019.
The aim of the present study was to investigate the role of intensity-modulated radiotherapy (IMRT) on the toxicity profile of patients treated with conservative surgery (CS) of the supraglottic (SG) region. Data on patients treated with CS and postoperative radiotherapy (PORT)-IMRT were prospectively collected. Results.
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