Publications by authors named "S K Kjaer"

Background: Maternal hormonal contraception use has been associated with childhood leukemia risk. However, studies are few and often based on self-reported information.

Methods: Using registry data from Denmark, Norway, and Sweden, we identified 3,183,316 children (born 1996-2018) and followed them from birth until leukemia diagnosis, censoring (death, emigration, other cancer, 20th birthday) or study closure (December 31st, 2017, 2018 or 2020).

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Whether fertility treatment increases the risk of ovarian cancer has been a concern for many decades, but previous research has yielded conflicting findings. We therefore investigated this association within a large population-based cohort study of infertile women aged 20-45 years and living in Denmark between 1995 and 2017, as identified in the Danish Infertility Cohort (n = 146,110). The study cohort was linked to nationwide registers to obtain information on fertility drug use, cancer diagnoses, covariates, emigration, and vital status was.

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Article Synopsis
  • The study analyzed cancer trends related to human papillomavirus (HPV) in Denmark from 2000 to 2022, focusing on cervical precancer, genital warts, and overall disease burden post-HPV vaccination.
  • Findings revealed a significant decline in age-standardized incidence rates (ASRs) for cervical precancer and genital warts, particularly among women, while HPV-associated cancers have been rising in men and non-cervical sites among women.
  • The conclusion emphasized that, even with vaccination efforts leading to decreased cases of certain HPV-related conditions, HPV-associated diseases continue to pose a public health challenge, especially among men.
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International stakeholders gathered in New Delhi, India, in December 2022 to share experiences on human papillomaviruses (HPV) prevention and control strategies. As part of a supplementary publication from the meeting proceedings, this paper describes secondary HPV prevention strategies highlighting the varying degrees of progress and challenges through case studies from Bhutan, India, and Türkiye. India has implemented national screening guidelines, primarily using visual inspection with acetic acid (VIA), but achieving a low coverage rate of 1.

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A pivotal study in women aged 16-26 years demonstrated that the nine-valent human papillomavirus (9vHPV) vaccine was efficacious against high-grade cervical dysplasia related to the HPV types covered by the vaccine. To evaluate whether effectiveness remains above 90% for up to 14 years post-vaccination, a long-term follow-up (LTFU) extension of the study was conducted in Denmark, Norway, and Sweden ( = 2,029). Interim findings at 12 years post-vaccination are reported.

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