Severe Diffuse Ulcerative Esophagitis Caused by Epstein-Barr Virus/Cytomegalovirus Coinfection in an Immunocompetent Individual.

Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are important causes of viral esophagitis mainly in immunocompromised individuals. Both viruses lead to development of focal ulcerations in the esophagus. While there have been rare case reports of esophagitis in immunocompetent individuals, there has not been a single reported case of coinfection with both CMV and EBV in an immunocompetent individual and presenting with diffuse esophageal ulceration.

Effectiveness of introducing fresh fruits in Anganwadi menu among children between 3-6 years in Mysuru city.

Introduction: Micronutrient malnutrition remains a huge public health problem, with the main issues lying with the lack of diet diversity, either lack or less of animal products, sparse amount of fruits and vegetables. Fruits are a very good source of vitamins and minerals to help in the growth and development of the child. There are a lot of implementation hurdles at the ground level.

The Oral Bioavailability of Vitamin B at Different Doses in Healthy Indian Adults.

Background/objectives: The bioavailability of crystalline vitamin B (B) through active absorption is reported to have a maximum capacity of 1.5-2.5 µg per dose.

The application of machine learning for treatment selection of unruptured brain arteriovenous malformations: A secondary analysis of the ARUBA trial data.

Objective: To build a supervised machine learning (ML) model that selects the best first-line treatment strategy for unruptured bAVMs.

Methods: A Randomized Trial of Unruptured Brain Arteriovenous Malformations (ARUBA) trial data was obtained from the National Institute of Neurological Disorders and Stroke (NINDS). A team of five clinicians examined the demographic, clinical, and radiological details of each patient at baseline and reached a consensus on the best first-line treatment for bAVMs.

Upstream targeting for the prevention of atrial fibrillation: Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)-rationale and study design.

Background: Despite advances in ablation and other therapies for AF, progression of atrial fibrillation (AF) remains a significant clinical problem, associated with worse prognosis and worse treatment outcomes. Upstream therapies targeting inflammatory or antifibrotic mechanisms have been disappointing in preventing AF progression, but more recently genetic and genomic studies in AF suggest novel cellular and metabolic stress targets, supporting prior studies of lifestyle and risk factor modification (LRFM) for AF. However, while obesity is a significant risk factor, weight loss and risk factor modification have not been successfully applied in a US population with AF.