SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques.

The latent viral reservoir remains the major barrier to HIV cure, placing the burden of strict adherence to antiretroviral therapy (ART) on people living with HIV to prevent recrudescence of viremia. For infants with perinatally acquired HIV, adherence is anticipated to be a lifelong need. In this study, we tested the hypothesis that administration of ART and viral Envelope-specific rhesus-derived IgG1 monoclonal antibodies (RhmAbs) with or without the IL-15 superagonist N-803 early in infection would limit viral reservoir establishment in SIV-infected infant rhesus macaques.

Evaluation of Healing Efficacy of Collagen Matrix and Connective Tissue Graft for Root Coverage Using Doppler Flowmetry: A Case Report.

The epitome of periodontal plastic surgical procedures is to achieve coverage of the denuded root surface and flawless esthetics. Connective tissue graft (CTG) along with coronally advanced flap (CAF) is the most frequent approach, which is considered a gold standard remedy. The procurement of CTG requires a second surgical site morbidity.

Feasibility of a Yoga Intervention in an Inpatient Limb Loss Rehabilitation Program.

Background: Limb loss is a life-changing event, which may be associated with limited mobility, pain, and low mood. Yoga interventions have been found to be beneficial for improving emotional wellness and pain in other patient populations. The benefits of including yoga in limb loss rehabilitation have not been well studied.