Publications by authors named "S K Jacobi"
Hypothermic oxygenated machine perfusion (HOPE) has emerged as a critical innovation in liver transplantation (LTx), offering significant protection against ischemia-reperfusion injury (IRI). This study focuses on quantifying and characterizing immune cells flushed out during HOPE to explore its effects on graft function and post-transplant outcomes. Fifty liver grafts underwent end-ischemic HOPE.
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- The study analyzed trends and factors influencing the use of palliative care among patients with metastatic upper tract urothelial carcinoma (mUTUC) by reviewing data from the National Cancer Database between 2004 and 2020.
- Out of 4,044 patients included, 22.5% received palliative care, and the utilization significantly increased from 15.0% in 2004 to 23.1% in 2019.
- Key predictors for receiving palliative care included a recent diagnosis year, prior nonsurgical treatments, and a prognosis of less than 6 months, while factors like older age and treatment at minority-serving hospitals were linked to lower palliative care uptake.
The role of MRI in the diagnosis of aseptic loosening following total hip arthroplasty.
Arch Orthop Trauma Surg
November 2024
Introduction: The role of advanced imaging in diagnosing aseptic implant loosening following total hip arthroplasty (THA) remains unclear. This study aimed to assess the diagnostic value of magnetic resonance imaging (MRI) in detecting aseptic loosening.
Methods: This was a retrospective review of 342 consecutive patients who underwent revision THA between July 2011 and April 2023 and had a pelvis MRI as part of the preoperative diagnostic evaluation.
Studies suggest steroidal alkaloids contribute to the health properties of tomato-rich diets. Untargeted studies have detected tomato steroidal alkaloid metabolites in plasma, tissues, and urine, but concentrations remain unknown. Here we utilize UHPLC-MS/MS to characterize 31 steroidal alkaloid metabolites representing 10 unique masses, and a validated UHPLC-MS method to quantify them in blood plasma.
View Article and Find Full Text PDFConducting external post-mortem examinations is an essential skill required of physicians in various countries, regardless of their specialization. However, the quality of these examinations has been a subject of continuous debates, and notable errors were reviled. In response to these shortcomings, a virtual reality (VR) application was developed at Halle's medical department in Germany, focusing on the scene of discovery and the completion of death certificates.
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