Porous Fe-Porphyrin as an Efficient Adsorbent for the Removal of Ciprofloxacin from Water.

Antibiotics are widely used in medicine, but they are not fully metabolized in the body and can end up in wastewater. Conventional wastewater treatment methods fail to completely remove antibiotic residues, which can then enter rivers and streams. Adsorption is a promising technique for removing antibiotics from wastewater, even at low concentrations.

Nickel-Cobalt Salen Organometallic Complexes Encapsulated in Mesoporous NaA Nanozeolite for Electrocatalytic Quantification of Ascorbic Acid and Paracetamol.

Goal of current study was fabrication of novel voltammetric nanosensor for the synchronize quantification of ascorbic acid (AA) and paracetamol (PAR) by nickel-cobalt salen complexes encapsulated in the supercages of NaA nanozeolite modified carbon paste electrode (NiCoSalenA/CPE). For this purpose, NiCoSalenA nanocomposite was firstly prepared and characterized by various methods. Also, cyclic voltammetry (CV), choronoamperometry (CHA) and differential pulse voltammetry (DPV) were utilized to evaluate performance of the modified electrodes.

Hybrid consensus and k-nearest neighbours (kNN) strategies to classify dual BRD4/PLK1 inhibitors.

A novel decision-making procedure is proposed here for the first time to identify active/inactive and selective/non-selective dual inhibitors using consensus approaches and pools of k-nearest neighbours (kNN) classifications instead of individual models. Dual BRD4/PLK1 inhibition with adequate selectivity is a potential therapeutic strategy for targeting tumour cells in high-risk patients. We report the unique way to identify both active and selective dual BRD4/PLK1 inhibitors using consensus and kNN strategies together with two sources of receptor-based and ligand-based information which are the ranked binding energies of residues and important molecular features, respectively.

Simultaneous determination of acetaminophen, pramipexole and carbamazepine by ZSM-5 nanozeolite and TiO nanoparticles modified carbon paste electrode.

In this present paper, a simple voltammetric method has been reported for the simultaneous determination of acetaminophen (AC), pramipexole (PRX) and carbamazepine (CBZ) using ZSM-5 nanozeolite-TiO nanoparticles composite modified carbon paste electrode (ZSM-5/TiO/CPE). X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM) and N adsorption-desorption isotherm were used to characterize the structure of synthesized ZSM-5 nanozeolite. Also, cyclic voltammetry (CV), choronoamperometry and differential pulse voltammetry (DPV) were used to investigate the performance of the modified electrode.

UV-Vis Spectrophotometry and Multivariate Calibration Method for Simultaneous Determination of Theophylline, Montelukast and Loratadine in Tablet Preparations and Spiked Human Plasma.

Resolution of binary mixtures of theophylline (THEO), montelukast (MKST) and loratadine (LORA) with minimum sample pre-treatment and without analyte separation has been successfully achieved by multivariate spectrophotometric calibration, together with partial least-squares (PLS-1), principal component regression (PCR) and hybrid linear analysis (HLA). Data of analysis were obtained from UV-Vis spectra of three compounds. The method of central composite design was used in the ranges of 2-14 and 3-11 mg L for calibration and validation sets, respectively.