Relevance of proteomics and metabolomics approaches to overview the tumorigenesis and better management of cancer.

Proteomics and metabolomics, integral combination of OMICs platform are gaining prominence in cancer research to enhance scientific knowledge of bio-molecular interactions occurs in the cellular processes during cancer progression. This approach designed to identify potential tools for addressing the complexities of this multifaceted disease. This analysis focussed on the intricate interplay between proteins and metabolites within cancer cells and their surrounding microenvironment.

Do social relationships at work enhance creativity and innovative behavior? Role of psychological safety.

The study uses social exchange theory to examine how social relationships affect individual involvement in creativity at work and innovative behavior, mediated by psychological safety. The study disentangles the social relationships at work as informal and formal relationships in terms of two plausible theoretical variables, workplace friendliness and perceived affective climate respectively, for the above purpose. Over a period of three-months, data collection was conducted in the IT and ITeS industry, with a sample of 515 participants and 105 team leads, using a two-pronged approach involving data from both team leads and their subordinates.

Temporal changes of spinal microglia in murine models of neuropathic pain: a scoping review.

Neuropathic pain (NP) is an ineffectively treated, debilitating chronic pain disorder that is associated with maladaptive changes in the central nervous system, particularly in the spinal cord. Murine models of NP looking at the mechanisms underlying these changes suggest an important role of microglia, the resident immune cells of the central nervous system, in various stages of disease progression. However, given the number of different NP models and the resource limitations that come with tracking longitudinal changes in NP animals, many studies fail to truly recapitulate the patterns that exist between pain conditions and temporal microglial changes.

Improved Protocol for Efficient -Mediated Transient Gene Expression in L.

L. (Alfalfa) is a globally recognized forage legume that has recently gained attention for its high protein content, making it suitable for both human and animal consumption. However, due to its perennial nature and autotetraploid genetics, conventional plant breeding requires a longer timeframe compared to other crops.

Vaccine hesitancy: a structured review from a behavioral perspective (2015-2022).

Vaccine hesitancy, a complex behavioral phenomenon, poses a significant global health threat and has gained renewed attention amidst the COVID-19 pandemic. This paper scrutinized peer-reviewed literature on vaccine hesitancy published from 2015 to 2022, with a specific focus on behavioral perspectives, utilizing a Theories-Constructs-Variables-Contexts-Methods (TCVCM) framework. The study highlighted prominent theoretical approaches, abstract concepts, research variables, global contexts and academic techniques employed across a selected sample of 138 studies.