Publications by authors named "S Joseph Leibovich"

Article Synopsis
  • Minoritized youth in under-resourced neighborhoods often depend on emergency medical services (EMS) for care during behavioral health emergencies (BHEs), but law enforcement (LE) may use forceful methods during these situations.
  • A study in Alameda County, California, investigated the factors like race, ethnicity, neighborhood disadvantage, sex, and age that are linked to LE handcuffing during pediatric BHEs between 2012 and 2019.
  • Results showed that handcuffing occurred in 7.6% of pediatric BHE encounters, with Black children and those from neighborhoods with moderate to high disadvantage facing significantly higher odds of being handcuffed compared to their peers.
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Objective: Emergency medical services (EMS) transport for mental and behavioral health (MBH) emergencies occurs frequently in children, yet little is understood regarding prehospital physical restraint use despite the potential for serious adverse events. We aim to describe restraint use prevalence and primary impressions among children with MBH emergencies.

Methods: This is a retrospective cross-sectional study of children with MBH emergencies evaluated by Alameda County (ALCO), California EMS from January 1, 2012 to December 31, 2018.

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Background: Despite substantial illness burden and healthcare utilization conferred by pain from vaso-occlusive episodes (VOE) in children with sickle cell disease (SCD), disease-modifying therapies to effectively treat SCD-VOE are lacking. The aim of the Sickle Cell Disease Treatment with Arginine Therapy (STArT) Trial is to provide definitive evidence regarding the efficacy of intravenous arginine as a treatment for acute SCD-VOE among children, adolescents, and young adults.

Methods: STArT is a double-blind, placebo-controlled, randomized, phase 3, multicenter trial of intravenous arginine therapy in 360 children, adolescents, and young adults who present with SCD-VOE.

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Children with sickle cell disease (SCD) commonly experience vaso-occlusive pain episodes (VOE) due to sickling of erythrocytes, which often requires care in the emergency department. Our objective was to assess the use and impact of intranasal fentanyl for the treatment of children with SCD-VOE on discharge from the emergency department in a multicenter study. We conducted a cross-sectional study at 20 academic pediatric emergency departments in the United States and Canada.

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