Navigating the landscape of HPV-associated cancers: From epidemiology to prevention.

Human Papillomavirus (HPV) is a widespread infection associated with various cancers, including cervical, oropharyngeal, anal, and genital cancers. This infection contributes to 5 % of global cancer cases annually, affecting approximately 625,600 women and 69,400 men. Cervical cancer remains the most prevalent HPV-linked cancer among females, with the highest incidence seen in low and middle-income countries (LMICs).

Ectopic Follicular Variant of Papillary Thyroid Carcinoma in Anterior Neck Region with a Normal Thyroid Gland-A Rare Entity.

Ectopic thyroid tissue is defined as thyroid tissue that is present at a location other than its normal anatomical location. It can have any pathological condition that could impact the orthotopic thyroid gland. However, ectopic thyroid tissue seldom becomes malignant, and the occurrence of a follicular variant of papillary carcinoma in ectopic thyroid is much more unusual.

Spindle cell variant of papillary thyroid carcinoma: A diagnostic challenge - A rare case report with brief review of literature.

Objective: Primary Spindle cell tumors of the thyroid are very rare and comprise a myriad of differential diagnoses ranging from reactive proliferations to neoplastic processes. Differentiation amongst these rare entities is of utmost importance as it defines the prognosis and also guides future therapy.

Case Report: Hereby, we present a rare case of spindle cell variant of papillary thyroid carcinoma in a sixty-four-year-old female which posed a diagnostic challenge on histology.

Cytological Diagnosis of Pilomatrixoma and its Diagnostic Pitfalls.

Background: Pilomatrixoma (PMX) is a relatively uncommon benign cutaneous neoplasm arising from skin adnexa. It presents as a subcutaneous asymptomatic nodule mostly in the head and neck region and is frequently misdiagnosed by the clinicians. Although easily diagnosed on histopathology, the cytologic features of PMX are less distinctive, depending on the stage and evolution of disease and may mimic other benign or even malignant lesions.

A histopathological and immunohistochemistry analysis of endometrial lesions among women presenting with abnormal uterine bleeding.

Objectives: We aimed to histopathologically evaluate the morphological spectrum, apoptotic index (AI), and mitotic index (MI) of endometrial lesions in patients presenting with abnormal uterine bleeding (AUB).

Methods: A cross-sectional study was done over a period of 18 months where a total of 60 newly diagnosed cases of perimenopausal women presenting with AUB were included. All H and E stained pathology slides from the specimens were reviewed for initial histopathological evaluation and diagnosis.