The influence of cognitive reserve on ERP measures of selective visual attentional processing in older adults after mild traumatic brain injury.

Objective: Older adults have an increased risk of developing persistent cognitive complaints after mild traumatic brain injury (mTBI). Yet, studies exploring which factors protect older adults with mTBI from developing such complaints are rare. It has been suggested that one such factor may be cognitive reserve (CR), but it is unknown how CR influences cognition in this patient category.

SARS-COV-2 ORF9b Dysregulate Fibrinogen and Albumin Genes in a Liver Cell Line.

Background: Individuals experiencing severe cases of Coronavirus Disease 2019 (COVID-19) exhibited elevated fibrinogen levels and decreased albumin levels, potentially linked to the presence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) proteins. Consequently, our study endeavors to examine the impact of SARS-CoV-2 ORF9b on the expression of fibrinogen and albumin genes within the Hep-G2 cell line.

Methods: In this study, the Hep-G2 liver cell line was utilized alongside the plasmid pcDNA3.

Citrus trifoliata extract -loaded chitosan nanoparticles as a potential treatment for osteoarthritis: An in vitro evaluation.

Osteoarthritis (OA) presents a significant global health burden, necessitating innovative therapeutic strategies to address its multifaceted challenges. This study explores the potential of extract-loaded chitosan nanoparticles (CTECNPs) as a novel treatment modality for OA. The encapsulation of extract (CTE) within chitosan nanoparticles offers advantages such as enhanced bioavailability, sustained release kinetics, and targeted delivery to affected joints.

The effects of local delivery of laurus nobilis extract and adipose derived stem cells via electrospun gelatin scaffold on spinal cord injury inflammatoradscy response and its regeneration.

When subjected to injury, the spinal cord's inherent complexity poses significant challenges for effective healing. In this study, gelatin nanofibers loaded with Laurus nobilis extract were developed to serve as a delivery system for adipose-derived stem cells (ADSCs), aiming to explore its potential immunomodulatory effects in a rat model of spinal cord injury. Through a series of in vitro assessments including scanning electron microscopy imaging, cell viability, anti-inflammatory, cell adhesion, biodegradation, and hemocompatibility assays, the characteristics of the delivery system were thoroughly evaluated.