Publications by authors named "S Jacobsson"
Microbiology reference laboratories perform a crucial role within public health systems. This role was especially evident during the COVID-19 pandemic. In this Viewpoint, we emphasise the importance of microbiology reference laboratories and highlight the types of digital data and expertise they provide, which benefit national and international public health.
View Article and Find Full Text PDFBackground: There are limited treatment options for prosthetic joint infections (PJI) due to multidrug-resistant Staphylococcus epidermidis (MDRSE). Fosfomycin (FOF) has gained attention as a potential therapy, but there is a paucity of information on the phenotypic and genotypic susceptibility amongst S. epidermidis, including MDRSE.
View Article and Find Full Text PDFAcute myeloid leukemia (AML) with the t(7;12)(q36;p13) translocation occurs only in very young children and has a poor clinical outcome. The expected oncofusion between break point partners (motor neuron and pancreas homeobox 1 [MNX1] and ETS variant transcription factor 6 [ETV6]) has only been reported in a subset of cases. However, a universal feature is the strong transcript and protein expression of MNX1, a homeobox transcription factor that is normally not expressed in hematopoietic cells.
View Article and Find Full Text PDFArticle Synopsis
- The study explores gepotidacin, a new treatment for gonorrhea, and investigates genetic changes in the GyrA and ParC targets of gonococci using a large dataset of genomes.
- Key findings show that alterations at GyrA position A92 are rare, while changes at ParC position D86 are more common, but neither type resulted in resistance to gepotidacin.
- The authors emphasize the importance of monitoring potential antimicrobial resistance and using effective MIC testing methods to ensure gepotidacin remains effective against gonorrhea.