Publications by authors named "S JAAKKOLA"
Background: After percutaneous coronary intervention (PCI), patients at high bleeding risk (HBR) according to The Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria have increased risk for ischemic complications. The underlying cause is not well documented. The aim of this study was to assess the ischemic risk among ST-elevation myocardial infarction (STEMI) patients classified as HBR according to the ARC-HBR and to identify individual risk factors.
View Article and Find Full Text PDFPerformance of the ARC-HBR Criteria in ST-Elevation Myocardial Infarction. Significance of Smoking as an Additional Bleeding Risk Factor.
Eur Heart J Qual Care Clin Outcomes
November 2024
Background And Aims: The Academic Research Consortium for High Bleeding Risk Criteria (ARC-HBR) are recommended by guidelines for bleeding risk assessment in ST-elevation myocardial infarction (STEMI). The aim of this study was to identify possible other risk factors and adjust the original ARC-HBR criteria for confounders.
Methods: All consecutive STEMI patients managed in a Finnish tertiary hospital between 2016-2022 were identified using a database search.
Objectives: Elevations of cardiac troponin T (cTnT) levels are common after strenuous exercise. We assessed whether the composition of cTnT release after marathon race differs from that of acute myocardial infarction (MI).
Methods: Troponin composition was analysed in plasma samples taken from 45 runners after marathon race and from 84 patients with type 1 MI.
Novel troponin fragmentation assay to discriminate between Takotsubo syndrome and acute myocardial infarction.
Eur Heart J Acute Cardiovasc Care
December 2024
Article Synopsis
- Cardiac troponin levels, elevated in Takotsubo syndrome (TTS), show significant overlap with acute myocardial infarction (MI), prompting a study on their fragmentation.
- The study measured long forms of cardiac troponin T (cTnT) in TTS (24 patients) versus Type 1 MI (84 patients), finding a notably lower troponin ratio in TTS, which indicates different cTnT fragmentation patterns.
- Results suggest that the troponin ratio is more effective than total cTnT in differentiating between TTS and MI, highlighting its potential as a diagnostic tool for elevated cTnT levels.
Article Synopsis
- The study investigates the long-term prognosis of patients suspected of having pulmonary embolism (PE), focusing on various biomarkers' predictive performance.
- Among 1,001 patients, about 22% were diagnosed with PE, and both groups exhibited a high mortality rate over nearly four years of follow-up.
- Key findings indicate that elevated NT-proBNP and C-reactive protein levels at hospital admission are linked to higher mortality in PE patients, while several biomarkers also predict mortality in patients without PE, emphasizing the need for careful risk assessment and alternative diagnoses.*