Publications by authors named "S J Zeichner"
The organic carbon content of ancient rocks provides a fundamental record of the biosphere on early Earth. For over 50 y, the high organic content of Archean (>2.5 Ga) mudrocks has puzzled geologists and evolutionary biologists, because high biological primary productivity was unexpected for the nascent biosphere before the rise of O.
View Article and Find Full Text PDFUnlabelled: Many mechanisms responsible for COVID-19 pathogenesis are well-established, but COVID-19 includes features with unclear pathogenesis, such as autonomic dysregulation, coagulopathies, and high levels of inflammation. The receptor for the SARS-CoV-2 spike protein receptor-binding domain (RBD) is angiotensin-converting enzyme 2 (ACE2). We hypothesized that some COVID-19 patients may develop antibodies that have a negative molecular image of RBD sufficiently similar to ACE2 to yield ACE2-like catalytic activity-ACE2-like abzymes.
View Article and Find Full Text PDFVaccines are essential tools to prevent infection and control transmission of infectious diseases that threaten public health. Most infectious agents enter their hosts across mucosal surfaces, which make up key first lines of host defense against pathogens. Mucosal immune responses play critical roles in host immune defense to provide durable and better recall responses.
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- Polycyclic aromatic hydrocarbons (PAHs) make up about 20% of carbon in the interstellar medium and can form under various conditions, including in hot circumstellar environments and cold interstellar clouds.
- Isotopic analysis of PAHs from asteroid Ryugu and meteorite Murchison shows that some PAHs, like naphthalene, fluoranthene, and pyrene, have higher carbon isotopic values than expected, indicating they likely formed in the interstellar medium rather than in hot environments.
- In contrast, the PAHs phenanthrene and anthracene from Ryugu display isotopic values that suggest they were formed through higher-temperature reactions.
Article Synopsis
- Current training methods for head and neck surgery lack realistic anatomical models, making it difficult to replicate complex surgical conditions.
- The Realistic Anatomical Condition Experience (RACE) model offers a solution by using a 3D-printed design based on real surgical data, allowing for more effective training.
- By making the STL file available as open source, RACE models could transform surgical education by promoting the use of realistic simulations over traditional methods.