Publications by authors named "S J Wahl"

Introduction: The incidence and prevalence of infections with non-tuberculous mycobacteria such as (Mav) are increasing. Prolonged drug regimens, inherent antibiotic resistance, and low cure rates underscore the need for improved treatment, which may be achieved by combining standard chemotherapy with drugs targeting the host immune system. Here, we examined if the diabetes type 2 drug metformin could improve Mav-infection.

View Article and Find Full Text PDF

Purpose: The postoperative occurrence of corneal guttae (CG) in patients after Descemet membrane endothelial keratoplasty (DMEK) can lead to a significant reduction in visual acuity (VA) with the subsequent need for repeat DMEK. Therefore, the aim of this study was to analyze the prevalence and clinical significance of CG in transplanted corneas after DMEK.

Methods: The prevalence and progression of CG after DMEK of 1657 patients were examined using endothelial specular microscopy images.

View Article and Find Full Text PDF
Article Synopsis
  • Humans struggle to see low-contrast objects during sudden changes in brightness, putting them at risk until their vision adapts.
  • A virtual reality simulation was developed to study how people detect low-contrast stimuli under different lighting conditions.
  • Results showed faster detection times when using self-tinting lenses during brightness decreases, indicating potential benefits for designing visual aids.
View Article and Find Full Text PDF

Summary: We present py_cFBA, a Python-based toolbox for conditional flux balance analysis (cFBA). Our toolbox allows for an easy implementation of cFBA models using a well-documented and modular approach and supports the generation of Systems Biology Markup Language models. The toolbox is designed to be user-friendly, versatile, and freely available to non-commercial users, serving as a valuable resource for researchers predicting metabolic behaviour with resource allocation in dynamic-cyclic environments.

View Article and Find Full Text PDF