Publications by authors named "S J Vasquez"

Cardiovascular diseases increasingly impact youth, with early development of risk factors such as obesity, hypertension, and inadequate nutrient intake. Proper nutrient intake and physical fitness are vital for reducing these risks, especially in pediatric populations. This study explores the connection between physical fitness, metabolic risk, and nutrient status among 1656 Chilean schoolchildren from diverse socio-economic backgrounds.

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  • Cardiac tamponade (CT) has a unique presentation in patients with pulmonary hypertension (PH), and this study aimed to assess the outcomes of CT in patients with or without PH using a large inpatient database from 2016 to 2020.
  • Out of 110,285 patients with CT, those with PH were generally older, more likely to be female, and had a higher incidence of coexisting conditions like hypertension and chronic heart failure.
  • The study found that PH is linked to higher in-hospital mortality and complications, with patients with PH less likely to receive beneficial treatments like pericardiocentesis, despite it being associated with lower mortality rates.
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Background: Until recently, breastfeeding has been contraindicated for women living with HIV (WHIV) in the U.S. However, given the numerous health benefits of breastfeeding, recommendations have changed to support parental choice to breastfeed through shared decision-making.

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  • Haspin phosphorylates histone H3 threonine 3 (H3T3), which is crucial for recruiting the chromosomal passenger complex and proper cell cycle progression during mitosis.
  • Researchers used cryo-EM to reveal how Haspin binds to nucleosomes, showing that it uniquely interacts with nucleosomal DNA rather than histone proteins.
  • The study identifies important basic residues in Haspin that are necessary for both phosphorylation of histone H3 and its binding to mitotic chromatin, marking a novel approach to understanding histone-modifying enzymes.
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