Influence of an impacted estuary on the reproduction of an endangered endemic fish.

Health and nutrition of individuals are tied to reproductive success, which determines population viability. Environmental variability and anthropogenic effects can affect the health and nutrition of a species leading to reproductive repercussions which can hinder recovery of endangered populations. Indices of health and nutrition were examined for an imperiled species, delta smelt, Hypomesus transpacificus, in relation to their reproductive status to evaluate the effects of hydrologic conditions in the San Francisco Estuary and Sacramento-San Joaquin Delta.

Insights from a year of field deployments inform the conservation of an endangered estuarine fish.

Freshwater fishes are increasingly facing extinction. Some species will require conservation intervention such as habitat restoration and/or population supplementation through mass-release of hatchery fish. In California, USA, a number of conservation strategies are underway to increase abundance of the endangered Delta Smelt (); however, it is unclear how different estuarine conditions influence hatchery fish.

Oil palm leaf protein hydrolysate and its novel peptides as alternative plant-based α-glucosidase inhibitors.

Diabetes, particularly type II, is a global health concern, with current treatments like α-glucosidase inhibitors often causing gastrointestinal side effects. This study explored the antihyperglycemic potential of crude protein hydrolysate from oil palm leaves (OPL) as a plant-based α-glucosidase inhibitor. OPL protein hydrolysate was extracted under acidic, neutral, and alkaline conditions, and their α-glucosidase inhibitory activity was assessed.

Islands of genomic stability in the face of genetically unstable metastatic cancer.

Introduction: Metastatic cancer affects millions of people worldwide annually and is the leading cause of cancer-related deaths. Most patients with metastatic disease are not eligible for surgical resection, and current therapeutic regimens have varying success rates, some with 5-year survival rates below 5%. Here, we test the hypothesis that metastatic cancer can be genetically targeted by exploiting single base substitution mutations unique to individual cells that occur as part of normal aging prior to transformation.