Publications by authors named "S J Taylor"

Background: Immunisation in pregnancy against pertussis can reduce severe disease in infancy. There are few data on the safety and immunogenicity of vaccines given to pregnant women living with HIV and their infants. We aimed to describe the safety and immunogenicity of a tetanus-diphtheria-acellular pertussis (TdaP) vaccine containing genetically detoxified pertussis toxin given to pregnant women living with HIV and the effect of the vaccine on infant whole-cell pertussis vaccine responses.

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Article Synopsis
  • A study was conducted to evaluate the effects of malaria infection during the first trimester of pregnancy on adverse outcomes for mothers and babies in Kenya, Zambia, and the Democratic Republic of the Congo.
  • Using rigorous testing methods, researchers found specific risks such as higher rates of preterm birth and anemia later in pregnancy among affected women.
  • The findings suggest that first-trimester malaria is linked to increased prevalence of anemia and highlight the need for more research on its impact on other pregnancy complications like preterm birth and low birth weight.
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Objectives: Insertional Achilles tendinopathy is a common and disabling condition. This trial aimed to determine the feasibility of conducting a parallel group randomised trial to evaluate the efficacy of heel lifts compared to a sham intervention for reducing pain intensity associated with insertional Achilles tendinopathy.

Methods: Twenty-six people with insertional Achilles tendinopathy were randomised to either the heel lift group or sham intervention group.

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Background Aims: Biliary atresia (BA) entails an inflammatory sclerosing lesion of the biliary tree, with prominent fibrosis in infancy. Previous studies revealed neutrophil-activating IL-8 and neutrophil extracellular traps (NETs) positively correlated with bilirubin and risk of liver transplant. The aims of this study were to determine the mechanism of NET formation (NETosis) in BA and if NETs induce stellate cell activation.

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