Publications by authors named "S J Sudharshan"

For prenatal screening, ultrasound (US) imaging allows for real-time observation of developing fetal anatomy. Understanding normal and aberrant forms through extensive fetal structural assessment enables for early detection and intervention. However, the reliability of anomaly diagnosis varies depending on operator expertise and device limits.

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Purpose: To study and compare the clinical characteristics and outcome of ocular syphilis between HIV positive and HIV negative patients.

Methods: Retrospective hospital-based case series from a tertiary eye care hospital in India. Patients with uveitis and positive syphilis serology were included.

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Purpose: To describe the clinical profile and complications of diabetic retinopathy (DR) and uveitis in patients with coexisting conditions and to derive associations based on site of primary inflammation, stage of DR, and complications of each.

Design: Single-center, cross-sectional observational study.

Participants: Sixty-six patients with coexisting DR and uveitis.

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Article Synopsis
  • This study investigates the use of tofacitinib, an oral medication, in nine pediatric patients with treatment-resistant uveitis and one with scleritis, focusing on its effectiveness and safety.* -
  • The patients, primarily affected by juvenile idiopathic arthritis, showed significant improvement, with most achieving remission and no systemic side effects reported during the follow-up period of around 278 days.* -
  • The findings suggest that tofacitinib could serve as a beneficial second-line treatment for pediatric uveitis, particularly in low- and middle-income countries.*
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Tachycardia-mediated cardiomyopathy is an established cause of left ventricular dysfunction. The development of cardiomyopathy depends on type, rate, and duration of tachyarrhythmia. Early recognition and treatment are critical in preventing left ventricular dysfunction and heart failure.

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