Publications by authors named "S J Raasveld"
Background: Current guidelines discourage prophylactic plasma use in non-bleeding patients. This study assesses global plasma transfusion practices in the intensive care unit (ICU) and their alignment with current guidelines.
Study Design And Methods: This was a sub-study of an international, prospective, observational cohort.
Background: Liberal or overtransfusion (OT) may be regarded as "inappropriate," but it is not reported as a transfusion-related adverse event. A definition of OT is lacking. OT may include overdosing of components, giving the incorrect component, or unnecessary administration without evidence of need for transfusion.
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- VA-ECMO (veno-arterial extracorporeal membrane oxygenation) is used to treat severe cardiac failure and can restore overall blood circulation, but its impact on small blood vessel function is still unclear.
- A systematic review of the literature (1215 studies sourced, 11 included) focused on how VA-ECMO affects microcirculation, measuring factors like small vessel density and blood flow.
- Initial findings suggest that microcirculatory function improves within hours for survivors of cardiac events post-ECMO, but this improvement levels off; more extensive research is needed to confirm these effects over time.
Background: Reported bleeding incidences following central venous catheter (CVC) placement highly depend on methods of bleeding assessment. To determine the direction and magnitude of the bias associated with retrospective data collection, we used data from the PACER randomized controlled trial and a previous retrospective cohort study.
Study Design And Methods: A patient-level comparison of CVC-related bleeding severity was made among (1) the prospectively collected clinical bleeding assessment of the PACER trial, (2) centralized assessment of CVC insertion site photographs, and (3) retrospective chart review.
Article Synopsis
- RBC transfusions are a frequent intervention in ICUs, yet there's a gap in understanding how hemoglobin (Hb) thresholds for transfusion are applied in practice.
- An international study analyzed transfusion practices in 233 ICUs across 30 countries, including 3,643 adult patients from March 2019 to October 2022.
- Of the patients studied, 25% received RBC transfusions, with variations in transfusion rates observed across different ICUs, countries, and continents, highlighting diverse clinical practices.