Redefining the limits of actuating fibers via mesophase control: From contraction to elongation.

The development of fibrous actuators with diverse actuation modes is expected to accelerate progress in active textiles, robotics, wearable electronics, and haptics. Despite the advances in responsive polymer-based actuating fibers, the available actuation modes are limited by the exclusive reliance of current technologies on thermotropic contraction along the fiber axis. To address this gap, the present study describes a reversible and spontaneous thermotropic elongation (~30%) in liquid crystal elastomer fibers produced via ultraviolet-assisted melt spinning.

Korean Gastric Cancer Association-Led Nationwide Survey on Surgically Treated Gastric Cancers in 2023.

Purpose: Since 1995, the Korean Gastric Cancer Association (KGCA) has been periodically conducting nationwide surveys on patients with surgically treated gastric cancer. This study details the results of the survey conducted in 2023.

Materials And Methods: The survey was conducted from March to December 2024 using a standardized case report form.

RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia.

Myeloid malignancies are heterogenous disorders characterized by distinct molecular drivers but share convergence of oncogenic signaling pathways and propagation by ripe pro-inflammatory niches. Here, we establish a comprehensive transcriptional atlas across the spectrum of myeloproliferative neoplasms (MPN) and secondary acute myeloid leukemia (sAML) through RNA-sequencing of 158 primary samples encompassing CD34+ hematopoietic stem/progenitor cells and CD14+ monocytes. Supported by mass cytometry (CyTOF) profiling, we reveal aberrant networks of PI3K/AKT/mTOR signalling and NFκB-mediated hyper-inflammation.

Association Between the Timing of Coronary Angiography, Targeted Temperature Management, and Neurological Outcomes After Out-of-Hospital Cardiac Arrest: A Nationwide Population-Based Registry Study in Korea.

Background: Coronary angiography (CAG) and targeted temperature management (TTM) may improve clinical outcomes after out-of-hospital cardiac arrest. This study aimed to assess whether the intervention effects differed according to timing and percutaneous coronary intervention (PCI) performance.

Methods And Results: Adult patients with presumed cardiac cause who underwent CAG and TTM within 24 hours following out-of-hospital cardiac arrest were included from the Korean nationwide out-of-hospital cardiac arrest registry.