Global distribution, diversity, and ecological niche of Picozoa, a widespread and enigmatic marine protist lineage.

Background: The backbone of the eukaryotic tree of life contains taxa only found in molecular surveys, of which we still have a limited understanding. Such is the case of Picozoa, an enigmatic lineage of heterotrophic picoeukaryotes within the supergroup Archaeplastida, which has emerged as a significant component of marine microbial planktonic communities. To enhance our understanding of the diversity, distribution, and ecology of Picozoa, we conduct a comprehensive assessment at different levels, from assemblages to taxa, employing phylogenetic analysis, species distribution modeling, and ecological niche characterization.

Effects of stress-related neuromodulators on amygdala and hippocampus resting state functional connectivity.

Background: The human stress response is characterized by increases in neuromodulators, including norepinephrine (NE) and cortisol. Both neuromodulators can enter the brain and affect neurofunctional responses. Two brain areas associated with stress are the amygdala and the hippocampus.

The effects of yohimbine and hydrocortisone on selective attention to fearful faces: An fMRI study.

Introduction: Selective attention to salient emotional information can enable an advantage in the face of danger. The present study aims to investigate the influence of the stress neuromodulators, norepinephrine and cortisol, on selective attention processes to fearful faces and its neuronal activation.

Methods And Materials: We used a randomized, double-blind, placebo-controlled design.

Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment.

Human genome-wide association studies (GWAS) suggest a functional role for central glutamate receptor signaling and plasticity in body weight regulation. Here, we use UK Biobank GWAS summary statistics of body mass index (BMI) and body fat percentage (BF%) to identify genes encoding proteins known to interact with postsynaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and -methyl-d-aspartate (NMDA) receptors. Loci in/near discs large homolog 4 () and protein interacting with C kinase 1 () reached genome-wide significance ( < 5 × 10) for BF% and/or BMI.

Co-infection of two eukaryotic pathogens within clam populations in Arcachon Bay.

The parasitic species (= ) (Perkinsea, Alveolata) infects a wide range of mollusc species and is responsible for mortality events and economic losses in the aquaculture industry and fisheries worldwide. Thus far, most studies conducted in this field have approached the problem from a "one parasite-one disease" perspective, notably with regards to commercially relevant clam species, while the impact of other species should also be considered as it could play a key role in the disease phenotype and dynamics. Co-infection of and has already been sporadically described in Manila clam populations in Europe.