Parallels Between Cupping in Traditional Chinese Medicine and in Native American Cultures.

Background: Traditional Chinese medicine (TCM) practices such as acupuncture and cupping have been practiced for thousands of years and recently gained more popularity and recognition because of their benefits. However, these practices are not unique to Eastern cultures and countries. The healing practices of folk healers like the of Indigenous communities in Latin America share striking similarities to their TCM counterparts, although not much literature exists on this topic.

The Neuroprotective Effect of the X Protein of Orthobornavirus Bornaense Type 1 in Amyotrophic Lateral Sclerosis.

In amyotrophic lateral sclerosis (ALS), early mitochondrial dysfunction may contribute to progressive motor neuron loss. Remarkably, the ectopic expression of the Orthobornavirus bornaense type 1 (BoDV-1) X protein in mitochondria blocks apoptosis and protects neurons from degeneration. Therefore, this study examines the neuroprotective effects of X protein in an ALS mouse model.

Overexpression of Egr1 Transcription Regulator Contributes to Schwann Cell Differentiation Defects in Neural Crest-Specific Knockout Mice.

Adenosine deaminase acting on RNA 1 (ADAR1) is the principal enzyme for the adenosine-to-inosine RNA editing that prevents the aberrant activation of cytosolic nucleic acid sensors by endogenous double stranded RNAs and the activation of interferon-stimulated genes. In mice, the conditional neural crest deletion of reduces the survival of melanocytes and alters the differentiation of Schwann cells that fail to myelinate nerve fibers in the peripheral nervous system. These myelination defects are partially rescued upon the concomitant removal of the Mda5 antiviral dsRNA sensor in vitro, suggesting implication of the Mda5/Mavs pathway and downstream effectors in the genesis of mutant phenotypes.

A Systematic Review of the Efficacy of Compression Wraps as an Anxiolytic in Domesticated Dogs.

Many domesticated dogs show signs of anxiety, negatively impacting their own and their owner's mental and physical health. A systematic review evaluating whether pressure wraps decrease clinical signs of anxiety in dogs was completed to identify relevant studies. The main outcomes of interest included behavioral and physiological measures.

Investigating mechanical properties for developing a human infant cranial bone surrogate in pediatric craniofacial surgery.

Beyond the surgeon's feedback on bone behavior in the operating room, there is a paucity of data present in the literature on the mechanical properties of pediatric calvarial bone. The present study tested the calvarial bone of four species (Adult Humans, Dog, Pig, and Monkey) to find the mechanical properties. Three types of tests were performed; flexural, compression, and torsion to mimic how bone is handled during the surgery and the results were further compared with the existing published data for human pediatric calvarium.