Publications by authors named "S J Littlewood"
Background: Coronary computed tomography angiography (CCTA) is recommended as the first-line diagnostic imaging modality in low-to-intermediate-risk individuals suspected of stable coronary artery disease (CAD). However, CCTA exposes patients to ionizing radiation and potentially nephrotoxic contrast agents. Invasive coronary angiography is the gold-standard investigation to guide coronary revascularisation strategy; however, invasive procedures incur an inherent risk to the patient.
View Article and Find Full Text PDFMesalazine-induced myocarditis in a patient with ulcerative colitis: a case report.
Eur Heart J Case Rep
September 2024
Background: Mesalazine is an established first-line therapy for inflammatory bowel disease (IBD) and remains the mainstay of treatment for mild to moderate ulcerative colitis (UC). Both mesalazine and UC are rare but recognized causes of myopericarditis. Cardiac magnetic resonance (CMR) is a non-invasive method of assessing for myopericarditis.
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- A new imaging technique was developed for 3D whole-heart mapping using motion compensation at a lower magnetic field strength (0.55T) to improve image resolution and quality while patients breathe normally.
- This technique involves acquiring three different water/fat volumes and utilizes image navigators for better motion correction and image reconstruction; initial tests on healthy volunteers showed promising results compared to traditional methods.
- Validation results indicated high accuracy and quick scan times (about 7 minutes), with the new method providing measurements comparable to traditional sequences in terms of myocardial T1 and T2 values, ensuring its potential for clinical use.
Article Synopsis
- - This study assessed the effectiveness of bone anchored maxillary protraction (BAMP) in treating class III skeletal malocclusion in children (ages 11-14) compared to a control group receiving no treatment, focusing on surgery necessity, dental changes, and psychological effects.
- - Conducted as a randomized controlled trial in six UK hospitals, 57 participants were divided into two groups: 28 received BAMP treatment, while 29 were in the no-treatment control group; measurements were taken at multiple points over 3 years.
- - Results showed significant improvements in skeletal and dental measures for the BAMP group at the 18-month mark, with a lower percentage of participants in this group feeling they needed surgery at the 3-year
Background: Without a phase of retention after successful orthodontic treatment, teeth tend to 'relapse', that is, to return to their initial position. Retention is achieved by fitting fixed or removable retainers to provide stability to the teeth while avoiding damage to teeth and gums. Removable retainers can be worn full- or part-time.
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