Publications by authors named "S J Lackey"
Soybean improvement has entered a new era with the advent of multi-omics strategies and bioinformatics innovations, enabling more precise and efficient breeding practices. This comprehensive review examines the application of multi-omics approaches in soybean-encompassing genomics, transcriptomics, proteomics, metabolomics, epigenomics, and phenomics. We first explore pre-breeding and genomic selection as tools that have laid the groundwork for advanced trait improvement.
View Article and Find Full Text PDFSeveral barriers exist in Alberta, Canada to providing accurate and accessible diagnoses for patients presenting with acute knee injuries and chronic knee problems. In efforts to improve quality of care for these patients, an evidence-informed clinical decision-making tool was developed. Forty-five expert panelists were purposively chosen to represent stakeholder groups, various expertise, and each of Alberta Health Services' 5 geographical health regions.
View Article and Find Full Text PDFThe nursing shortage that is upon us is the result of a confluence of factors, some simple and some complex. Legacy solutions are not working. Recovery from the current situation involves examining and reshaping the nursing work environment.
View Article and Find Full Text PDFArticle Synopsis
- Corticosteroids relieve inflammatory low back pain primarily by targeting the glucocorticoid receptor (GR), but they also affect the mineralocorticoid receptor (MR), which is present in pain-related neurons.
- In this study, researchers selectively knocked out (KO) the MR in sensory neurons to explore its role in pain responses during a local inflammation model in mice.
- The results indicated that while MR antagonism reduced pain sensitivity, MR KO in sensory neurons did not produce the same effect, suggesting that MR's role in pain may involve both neuronal and non-neuronal interactions in the dorsal root ganglia.
Article Synopsis
- Low back pain (LBP) is a common issue that causes problems for people and costs a lot of money in healthcare.
- Alberta is trying to improve the way doctors treat LBP by creating a standardized plan based on the best medical practices.
- A group of healthcare experts worked together to make a tool that helps doctors assess and manage LBP patients better and faster.