Lacosamide as an Adjunctive Therapy in the Management of Refractory Neonatal Seizures: A Retrospective Study.

Objective: Neonatal seizures present significant treatment challenges, often requiring adjunctive antiseizure medications. This study aimed to evaluate the efficacy of lacosamide as an adjunctive antiseizure medication in managing refractory neonatal seizures.

Methods: The study included neonates up to 44 weeks of corrected gestational age who received lacosamide treatment at a level 4 neonatal intensive care unit between January 2015 and December 2023.

Déjà-vu sensation induced by cortical stimulation of the posterior cingulate cortex.

We report a case of a 19-year-old woman with drug-resistant focal epilepsy whose typical seizure semiology involved sensations of déjà-vu. She underwent intracranial stimulation, leading to déjà-vu upon stimulation of the posterior cingulate cortex (PCC). Most reports of induced déjà-vu and epilepsy-associated déjà-vu emphasize networks including temporal lobe, especially the rhinal cortices, as the generator of this phenomenon.

Secondary spontaneous pneumothorax as the presenting manifestation of filamin A-associated lung disease.

https://bit.ly/3ycAeCs.

Who wears the crown? Comparing 3D-printed resin crowns to preformed stainless steel crowns for restoring primary molars.

Design: A multi-centre randomised controlled trial was conducted with paediatric patients requiring crowns after pulp therapy. Participants were randomly divided into two groups: Stainless Steel Crown (SCC) (n = 28) and Resin Crown (RC) (n = 28). RCs were fabricated using a 3D printer with a standardised manufacturing process.

Pediatric Palliative Epilepsy Surgery: A Report From the Pediatric Epilepsy Research Consortium (PERC) Surgery Database.

Background: Epilepsy surgery is an underutilized resource for children with drug-resistant epilepsy. Palliative and definitive surgical options can reduce seizure burden and improve quality of life. Palliative epilepsy surgery is often seen as a "last resort" compared to definitive surgical options.