Publications by authors named "S J KANGAS"
Article Synopsis
- * A secondary analysis from previous trials found that linear growth and weight gain velocities in children with SAM were similar between the new simplified treatment and the standard treatment, despite using lower RUTF doses.
- * The results suggest that using a reduced RUTF dosage for treating SAM does not negatively impact linear growth or overall growth velocities, indicating that the simplified protocol is an effective option.
Treatment of acute malnutrition requires novel approaches to improve coverage, reduce costs and improve the efficiency of standard protocols that separate the management of moderate acute malnutrition (MAM) and severe acute malnutrition (SAM). The use of simplified, combined protocols to treat both MAM and SAM has drawn research and policy interest among global, regional and national stakeholders. However, the perspectives of local communities and health care workers regarding the use of protocols to treat acute malnutrition in a routine health care system are generally lacking.
View Article and Find Full Text PDFSalla disease (SD) is a lysosomal storage disease where free sialic acid (SA) accumulates in lysosomes due to the impaired function of a membrane protein, sialin. Synchrotron radiation-based scanning transmission soft X-ray spectromicroscopy (STXM) was used to analyze both SD patients' fibroblasts and normal human dermal fibroblasts (NHDF) from healthy controls. Both cell lines were also cultured with -acetyl-d-mannosamine monohydrate (ManNAc) to see if it increased SA concentration in the cells.
View Article and Find Full Text PDFTreatment of severe acute malnutrition aims at producing quick catch-up growth in children to decrease their short-term mortality risk. The extent to which catch-up growth is influenced by the amount of energy provided is unclear. This study assessed whether energy provided at admission is associated with catch-up ponderal growth among children with mid-upper arm circumference (MUAC) < 115 mm at admission.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to identify brain MRI patterns associated with pediatric genetic disorders linked to white matter abnormalities in Northern Finland, focusing on patients diagnosed before age 18.
- Researchers reviewed MRI scans from Oulu University Hospital collected over 29 years, ultimately analyzing 83 patients with 52 different genetic conditions that showed significant white matter issues.
- A majority (87%) of the children had abnormal MRI results, highlighting specific abnormalities like cerebral white matter changes and thinning of the corpus callosum, indicating that these patterns can help diagnose rare genetic disorders effectively.