Publications by authors named "S J Huffaker"
Background: There is an expanding unregulated market for a psychotropic compound called ∆-Tetrahydrocannabinol (delta-8-THC) that is being derived from hemp, but a summary of adverse events related to delta-8-THC has not been publicly reported.
Methods: This case series assessed adverse events reported by delta-8-THC users on the Reddit forum r/Delta8 and compared these to delta-8-THC AEs in the US Food and Drug Administration Adverse Event Reporting System (FAERS). Delta-8-THC and cannabis AEs reported in FAERS were also compared.
Background: When faced with a periprosthetic joint infection (PJI) following total knee arthroplasty, the treating surgeon must determine whether 2-stage revision or "liner exchange," aka debridement, antibiotics, exchange of the modular polyethylene liner, and retention of fixed implants (DAIR), offers the best balance of infection eradication versus treatment morbidity. We sought to determine septic re-revision risk following DAIR compared to initial 2-stage revision.
Methods: We conducted a cohort study using data from Kaiser Permanente's total joint replacement registry.
Background: Under the Affordable Care Act, hospitals receive reduced reimbursements for excessive 30-day readmissions. However, the Centers for Medicare and Medicaid Services does not consider social and behavioral variables in expected readmission rate calculations, which may unfairly penalize systems caring for socially disadvantaged patients, including patients with HIV.
Setting: Randomized controlled trial of patient navigation with or without financial incentives in HIV-positive substance users recruited from the inpatient setting at 11 US hospitals.
Background: Ecological momentary assessments (EMA) are data collection approaches that characterize behaviors in real-time. However, EMA is underutilized in alcohol and substance use research among men who have sex with men (MSM). The aim of this analysis is to explore the correlates of engagement in EMA text messages among substance-using MSM in San Francisco.
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- The study explored the feasibility of enrolling nondependent meth-using and binge-drinking men who have sex with men (MSM) in a pharmacologic trial, focusing on their acceptance and tolerance of targeted naltrexone compared to a placebo.
- Results showed high retention and satisfaction rates among participants, with no significant adverse events; however, differences in meth use and drinking were not observed overall.
- Naltrexone users demonstrated notable reductions in risky sexual behaviors and, particularly among frequent meth users, reductions in meth use and binge drinking days, indicating its potential as an effective intervention strategy.