Publications by authors named "S J Freedman"
Article Synopsis
- The study focuses on refractive changes observed in children aged 5 years who underwent cataract surgery with intraocular lens placement before age 2.
- It analyzed data from 96 children, comparing results between unilateral and bilateral cataract cases, as well as those operated on at different ages (1 to <7 months vs. 7-24 months).
- The findings indicated that children operated on between 1 to <7 months experienced significantly more refractive change compared to those operated on later, suggesting careful consideration is needed when selecting lens power and target refraction for younger patients.
Pancreatic cancer has the worst prognosis of all common tumors. Earlier cancer diagnosis could increase survival rates and better assessment of metastatic disease could improve patient care. As such, there is an urgent need to develop biomarkers to diagnose this deadly malignancy.
View Article and Find Full Text PDFBackground: Elexacaftor/tezacaftor/ivacaftor (ETI) is a highly effective therapy that improves lung disease in people with cystic fibrosis (pwCF), but its effect on glucose tolerance and insulin secretion is unclear.
Methods: PROMISE is a multicenter prospective, observational study of ETI in pwCF ≥12 years and at least one F508del allele. The PROMISE Endocrine sub-study (PROMISE-ENDO) enrolled participants at 10 CF Centers where hemoglobin A1c (HbA1c) was collected and 3-hour oral glucose tolerance tests (OGTT) conducted to examine glucose tolerance, glucose excursions, insulin secretory rates (deconvolution of C-peptide) and sensitivity (oral minimal model) prior to ETI and 12-18 months (mos) and 24-30 mos following ETI initiation.
Article Synopsis
- - This study examines how symptoms from sport-related concussions (SRC) and non-SRC recover in young children aged 5 to 12 years over a period of 12 weeks.
- - The research included 1,747 children from various pediatric emergency departments and analyzed their symptom changes using a standardized inventory to gather self-reported and parent-reported data.
- - The findings aim to provide insights into the differences in symptom recovery trajectories between younger children and highlight any variations based on the type of injury experienced.
Objectives: Chronic pancreatitis (CP) is a fibro-inflammatory disorder characterized by abdominal pain and exocrine and endocrine pancreatic insufficiency resulting in significant morbidity. This study evaluates the impact of geospatial parameters, assessed using the Social Vulnerability Index (SVI), a tool comprising sixteen social attributes, on CP outcomes, including opioid use.
Methods: We conducted a retrospective analysis of CP patients with available addresses followed at our pancreas center.