Enhancement of health beneficial bioactivities of bitter melon (Momordica charantia L.) by puffing.

Effects of puffing and extraction method on physical and biological efficacy of bitter melon was investigated. Puffing increased the Maillard reaction products, extraction yield, total phenolic and total flavonoid contents. Antioxidant activity was the highest at 980 kPa, but there was no significant difference between two extraction methods.

Corrigendum to "Laparoscopy-assisted trans gastric wedge resection: A safe treatment for gastric pyloric liposarcoma: A case report and literature review" [Heliyon 10 (9) (May 2024) e30410].

[This corrects the article DOI: 10.1016/j.heliyon.

Gastric Stenosis Four Years After Adjustable Gastric Band Removal Surgery-A Video Case Report.

Laparoscopic adjustable gastric banding (LAGB) is a type of bariatric surgery. Gastric stenosis or obstruction is a known complication of LAGB; however, its occurrence after band removal is extremely rare. A 60-year-old female, who had undergone LAGB 6 years earlier and band removal 4 years prior, presented to the hospital with recurrent vomiting.

High p16 expression in glioblastoma is associated with senescence phenotype and better prognosis.

Glioblastoma, isocitrate dehydrogenase (IDH)-wildtype (GBM), is the most malignant brain tumor in adults, with limited therapeutic intervention. Previous studies have identified a few prognostic markers for GBM, including the methylation status of O-methylguanine-DNA methyltransferase (MGMT) promoter, TERT promoter mutation, EGFR amplification, and CDKN2A/2B deletion. However, the classification of GBM remains incomplete, necessitating a comprehensive analysis.

In situ forming and self-crosslinkable protein hydrogels for localized cancer therapy and topical wound healing.

Proteins, inherently biocompatible and biodegradable, face a challenge in forming stable hydrogels without external chemical crosslinkers. Here, we construct a ring-shaped trimeric SpyTag-fused Proliferating Cell Nuclear Antigen Protein (ST-PCNA) as a core protein building block, and a dumbbell-shaped tandem dimeric SpyCatcher (SC-SC) as a bridging component. Self-crosslinked PCNA/SC-SC Protein (2SP) hydrogels are successfully formed by simply mixing the solutions of ST-PCNA and SC-SC, without chemical crosslinkers.