Publications by authors named "S J Dickinson"
Background: The credibility of nutritional research is dependent on the rigor with which studies are conducted and the ability for independent assessment to be performed. Despite the importance of these, more work is needed in the field of nutrition to buttress the trustworthiness of nutrition research.
Objective: To develop and apply a process for evaluating the rigor, reproducibility, and verifiability of nutritional research, using the relationship between potato consumption and Colorectal cancer (CRC) as a case study.
Article Synopsis
- BMS-202 is a small molecule with antitumor properties, and this study investigates its physical and chemical characteristics for potential use in topical applications, focusing on uniformity, stability, and safety.
- Various analytical methods such as SEM, DSC, HSM, Raman, and FTIR were used to analyze BMS-202, revealing its unique morphology, thermal behavior, and chemical consistency, while also measuring moisture content and uptake under different humidity levels.
- Safety tests on skin cell lines indicated that while high concentrations of BMS-202 are cytotoxic, lower doses are safe and do not compromise skin barrier integrity.
Objectives: During 2015-2018, a randomised controlled trial (RCT) evaluated eRAPID, an eHealth intervention designed to capture patient-reported symptoms online during cancer treatment. eRAPID provides patients with advice on when to self-manage or seek medical support. Clinicians accessed symptom reports within electronic patient records.
View Article and Find Full Text PDFBiological clocks and other molecular biomarkers of aging are difficult to implement widely in a clinical setting. In this study, we used routinely collected hematological markers to develop an aging clock to predict blood age and determine whether the difference between predicted age and chronologic age (aging gap) is associated with advanced aging in mice. Data from 2,562 mice of both sexes and three strains were drawn from two longitudinal studies of aging.
View Article and Find Full Text PDFArticle Synopsis
- The Lisfranc complex refers to the connection between the medial cuneiform and the second metatarsal base, commonly injured in high-impact activities.
- A study reviewed the outcomes of 99 patients who received surgical fixation for Lisfranc injuries, divided into those treated within 24 hours and those treated later.
- The results indicated that early surgical treatment did not lead to better outcomes compared to delayed fixation, although there was a slight increase in superficial infections in the early treatment group.