Publications by authors named "S J Caldwell"
Article Synopsis
- - The case report discusses treating a child with chronic non-bacterial osteomyelitis (CNO) in the jaw, which is a rare, non-infectious condition.
- - The patient showed symptoms like facial swelling and pain, and various medical tests helped confirm the diagnosis, though the cause was unclear.
- - Successful management of CNO involves a team-based approach among different specialties, and orthodontic treatment should be customized based on individual patient needs.
Background: Evaluating implementation of digital health interventions (DHIs) in practice settings is complex, involving diverse users and multistep processes. Proactive planning can ensure desired implementation determinants and outcomes are captured for hybrid studies, but operational guidance for DHI studies is limited.
Methods: We planned a cluster randomized, type II hybrid effectiveness-implementation trial testing PositiveLinks, a smartphone application for HIV care, compared to usual care (n = 6 sites per arm), among HIV outpatient sites in the DC Cohort Longitudinal HIV Study in Washington, DC.
Early learning and child care (ELCC) settings in Canada follow nutrition standards that outline food provisions, with many also encouraging responsive feeding practices that help to create a supportive environment for children. Caregivers who lack confidence in children's ability to regulate their own intake, or those who feel stressed about mealtime, may unknowingly engage in less responsive feeding practices. The CELEBRATE Feeding Approach is a flexible framework, driven by behaviour change theory, that builds on previous definitions and concepts of responsive feeding in ELCC environments.
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- This phase 1b study assessed the safety and effectiveness of cilofexor, a drug targeting farnesoid X receptors, in patients with compensated cirrhosis caused by primary sclerosing cholangitis over 12 weeks.
- Patients received increasing doses of cilofexor, and while most reported side effects like pruritus and fatigue, there were no serious adverse events.
- Results showed significant improvements in liver function markers, indicating that cilofexor may help manage cholestasis in these patients.
Article Synopsis
- - This study assessed the effectiveness of bone anchored maxillary protraction (BAMP) in treating class III skeletal malocclusion in children (ages 11-14) compared to a control group receiving no treatment, focusing on surgery necessity, dental changes, and psychological effects.
- - Conducted as a randomized controlled trial in six UK hospitals, 57 participants were divided into two groups: 28 received BAMP treatment, while 29 were in the no-treatment control group; measurements were taken at multiple points over 3 years.
- - Results showed significant improvements in skeletal and dental measures for the BAMP group at the 18-month mark, with a lower percentage of participants in this group feeling they needed surgery at the 3-year