Congenital Titinopathy: Comprehensive Characterization of the Most Severe End of the Disease Spectrum.

Unlabelled: Congenital titinopathy has recently emerged as one of the most common congenital muscle disorders.

Objective: To better understand the presentation and clinical needs of the under-characterized extreme end of the congenital titinopathy severity spectrum.

Methods: We comprehensively analyzed the clinical, imaging, pathology, autopsy, and genetic findings in 15 severely affected individuals from 11 families.

Normative percentile values for the TGMD-3 for Italian children aged 3-11+years.

Objectives: Sufficient gross motor skill proficiency is an essential prerequisite for the successful performance of sport-specific skills and physical activities. The Test of Gross Motor Development is the most common tool for assessing motor skills in paediatric populations, however, there is a lack of 'normative' data available against which children's scores can be compared. Normative data would enable the comparison of an individual's motor development to age-standardised norms.

Cardiorespiratory demands of firearms training instruction and 15m shuttle tests in British law enforcement.

Objectives: Law enforcement agencies require minimum fitness standards to safeguard their officers and training staff. Firearms instructors (FI) are expected to maintain the same standards as their operational counterparts. This study aimed to quantify the daily physiological demands placed on FI.

An improved endwall-injection technique for examining high-temperature ignition of lubricating oils in shock tubes.

Ignition of the lubricating fluid in a mechanical system is a highly undesirable and unsafe condition that can arise from the elevated temperatures and pressures to which the lubricant is subjected. It is therefore important to understand the fundamental chemistry behind its ignition to predict and prevent this condition. Lubricating oils, particularly those with a mineral oil base, are very complex mixtures of thousands of hydrocarbons.

Preparing Australian diabetes educators for practice: workforce perceptions of the credentialling pathway.

The Australian Credentialled Diabetes Educator (CDE) registered trademark signifies quality care and education to those with diabetes. A review of the Australian Diabetes Educators Association (ADEA) CDE pathway was undertaken to ensure the quality of the CDE credential. The purpose of this study was to examine perceptions of the diabetes education workforce on the current pathway for educating and qualifying CDEs for practice.