Publications by authors named "S Izaki"
Progressive multifocal leukoencephalopathy (PML) is a devastating demyelinating disease caused by JC virus (JCV), predominantly affecting patients with impaired cellular immunity. PML is a non-reportable disease with a few exceptions, making national surveillance difficult. In Japan, polymerase chain reaction (PCR) testing for JCV in the cerebrospinal fluid (CSF) is performed at the National Institute of Infectious Diseases to support PML diagnosis.
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- * In the U.S., apheresis mainly utilizes centrifugal separation, while Japan prefers a membrane separation method, complicating the application of ASFA guidelines in Japanese practice due to differing disease targets and treatment approaches.
- * A group of specialists in various medical fields collaborated to create a comprehensive guideline for apheresis in Japan, formatted as a user-friendly worksheet to assist medical professionals with the therapy, and emphasizing the need for regular updates to keep pace with advancing medical