Publications by authors named "S Iwasawa"
Article Synopsis
- * From 2018 to 2021, ticks were collected and analyzed for the presence of B. odocoilei, revealing a 12% overall prevalence in I. scapularis across central and eastern Canada, with higher rates in specific years.
- * The study highlights the stable establishment of B. odocoilei in tick populations and emphasizes the need for ongoing surveillance to better understand and manage disease transmission.
Objectives: Programmed cell death ligand 1 (PD-L1) expression is widely used to predict the effectiveness of PD-(L)1 inhibitors despite its imperfection. Previous studies suggested the utilization of various serum biomarkers; nonetheless, findings are inconclusive because of limited sample sizes or the focus on a single biomarker in many of these studies. This study analyzed multiplex serum biomarkers to explore their predictive ability in a large cohort of patients with advanced non-small-cell lung cancer (NSCLC) treated with a PD-L1 inhibitor in a real-world setting.
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- The study aimed to investigate the relationship between immune-related adverse events (irAEs) and the effectiveness of immune checkpoint inhibitor therapy in cancer patients, particularly focusing on overall and progression-free survival.
- In a cohort of 1,002 Japanese patients with advanced non-small cell lung cancer treated with atezolizumab, 19% experienced irAEs, predominantly skin disorders and interstitial lung disease.
- Results showed that patients with irAEs had better overall survival compared to those without, especially those with low-grade irAEs, indicating potential clinical benefits from irAEs in real-world settings, except for high-grade events unrelated to skin or endocrine disorders.
Article Synopsis
- A 73-year-old man was admitted to the hospital with a right pleural effusion, and imaging showed multifocal effusions, leading to drainage procedures.
- Actinomyces meyeri was identified in the pleural fluid, and despite initial antibiotic treatment, the patient required a surgical procedure to address empyema.
- After a successful operation and removal of the chest tube, the patient was discharged with a course of intravenous antibiotics followed by six months of oral antibiotics, as treatment for actinomycosis empyema typically lasts from 6 to 12 months.
Objectives: We aimed to determine whether remote cognitive training (CT) is feasible and has the potential to improve cognitive function and work performance in Japanese workers.
Methods: From June to September 2020, this intervention time series study enrolled workers aged 18-65 years from 10 companies located in a metropolitan area of Japan. Cognitive function tests and self-administered questionnaires were completed by the participants three times: at baseline, after 12 weeks of CT, and after a further 12 weeks following cessation.