[Characteristic of immune cell and morphology of deciduas by different types of urogenital infection in the first term of pregnancy].

In the early terms of pregnancy anti-infectious protection provides by NK-cells of deciduas. The distribution of immunocompetent cells in the deciduas of women at 6-8 week of gestation and different infections has been studied by immunohisyochemical method. The quantity of NK-cells with CD56 +/- CD16+ CD3- phenotype significant decreased at mycoplasmas infection.

[Cellular composition of decidua basalis infiltrate during early pregnancy in urogenital mycoplasma infection].

The composition and distribution of immunocompetent cells in human decidua basalis at 6-8 weeks of pregnancy was studied immunonohistochemically under normal conditions (control group) and in infection with different mycoplasma species (microbial number> 104 CFU). In all the groups studied, monocytes were most numerous cells; large granular lymphocytes (phenotype: CD56++CD16-CD3), macrophages (CD68+) and immunonegative lymphocytes were observed in equal proportions; the least numerous populations were those of NK-cells (CD56+/-CD16+), plasmocytes and granulocytes. No statistically significant differences were found between the content of these cells in all the investigated groups.

[Clinical and immunological characteristics of rubella in western Siberia].

Evaluations of immune system of 155 patients with rubella and 90 contacts with patients were examined. Detection of viral genetic material in blood, urine, and nasopharyngeal swabs has been performed using RT-PCR method. Clinical diagnosis has been confirmed by RT-PCR in 114 (73.

[Perinatal aspects of serological diagnosis in urogenital chlamydiosis].

The pregnancy course, labor, delivery and early neonatal period were studied in pregnant women with Chlamydia trachomatis infection as well as in their children. The levels of specific antibodies to Chlamydia trachomatis pgp 3 plasmid protein in maternal sera as well as perinatal complications were comparatively analyzed. According to the results, examination of anti-pgp3 antibodies is a highly specific and useful tool for the detection of Chlamydia trachomatis infection at its active stage in pregnant women.

[Azithromycin levels in the chorion tissue within the first three months of the pregnancy term].

The levels of azithromycin in the chorion tissue within the first 3 months of the pregnancy term (42 to 56 days post coitus) were determined. Three days after the use of azithromycin (Sumamed) the antibiotic concentration in the villi tissue was 0.065 to 0.