Single versus dual antiplatelet therapy impact on coagulation/thrombosis post PAD revascularization.

Objective: To evaluate and compare the impact of single- versus dual-antiplatelet (SAPT vs DAPT) therapy on coagulation profiles and postoperative outcomes in patients with peripheral arterial disease (PAD).

Methods: Patients with PAD undergoing lower extremity revascularization from December 2020 to August 2023 were prospectively enrolled in this cohort study and followed for one year to record the incidence of thrombotic events (TEs). These events include arterial graft/stent occlusion or stenosis, as identified through Doppler ultrasonography or angiography.

Aneurysm and subacute type a aortic dissection, in a pediatric patient with aortopathy.

Aortic dissection in pediatrics is an extremely rare condition, which is generally related to predisposing factors such as connective tissue disorders, congenital heart disease and systemic arterial hypertension. A 3-year-old girl, with a history of bicuspid aortic valve, hypoplasia of the aortic arch and repaired aortic coarctation at one month of age. She was admitted 2 months of atypical chest pain, dysphonia, and low tone of voice.

Heart transplantation in controlled donation after circulatory determination of death: the Italian experience.

Background: Donation after circulatory death (DCD) donation is becoming more and more popular worldwide. However, in this setting of donation, heart graft suffers from the ischemic injury related with the cardiac arrest. In Italy, the declaration of death with cardiac parameters requires the registration of electrocardiograph for twenty minutes resulting in a very prolonged grafts' warm ischemia time.

Evaluation of sex-based differences in below-the-knee plaque histology in patients who underwent amputation for chronic limb-threatening ischemia.

Objective: With the growing incidence of peripheral arterial disease (PAD) and the historic under-representation of female patients in cardiovascular trials, a comprehensive evaluation of sex-based variances in PAD presentation and treatment outcomes is needed. This study aims to evaluate sex-based differences in the vessel wall characteristics of patients who underwent amputation owing to critical limb-threatening ischemia to optimize personalized treatment planning and aid in the selection of endovascular devices for PAD patients.

Methods: A total of 35 lower limbs were collected from 34 patients with end-stage PAD undergoing major amputation.

Dynamics of fluorinated imide-based ionic liquids using nuclear magnetic resonance techniques.

There is increasing interest in studying molecular motions in ionic liquids to gain better insights into their transport properties and to expand their applications. In this study, we have employed the fast field cycling relaxometry and pulsed field gradient nuclear magnetic resonance techniques to investigate the rotational and translational dynamics of fluorinated imide-based ionic liquids (ILs) at different temperatures. We have studied a total of six ILs composed of the 1-butyl-3-methylimidazolium cation ([BMIM]) combined with chemically modified analogs of the bis((trifluoromethyl)sulfonyl)imide anion ([NTf] or [TFSI]).