Publications by authors named "S Iraklianou"

Aims: To report the results of the first national Health Examination Survey (HES) on the prevalence of diabetes, its pharmacologic treatment and level of control, as well as pre-diabetes in Greece.

Methods: Data were derived from the National Survey of Morbidity and Risk Factors (EMENO), in a randomly selected, representative sample of the adult Greek population. Sampling weights were applied to adjust for study design and post-stratification weights to match sample age/sex distribution to the population.

View Article and Find Full Text PDF

Background Type 2 diabetes mellitus is a risk factor for lower extremity arterial disease. Cilostazol expresses antiplatelet, anti-inflammatory, and vasodilator actions and improves the claudication intermittent symptoms. We investigated the efficacy and safety of adjunctive cilostazol to clopidogrel-treated patients with type 2 diabetes mellitus exhibiting symptomatic lower extremity arterial disease, in the prevention of ischemic vascular events and improvement of the claudication intermittent symptoms.

View Article and Find Full Text PDF

Aims: We evaluated the influence of CETP (rs5882 and rs708272), APOE (rs7412, rs429358) and LPL (rs328) gene polymorphisms on triglyceride (TG) response to oral fat tolerance test (OFTT) meal in patients with well-controlled type 2 diabetes mellitus (T2DM).

Methods: Fifty-one men underwent OFTT and according to postprandial TG response patients were divided into two subgroups (positive [TG ≥ 220 mg/dL, 31 patients] and negative [TG < 220 mg/dL, 20 patients]). All patients were genotyped, and study variants were detected using polymerase chain reaction (PCR) and restricted fragment length polymorphism (RFLP) analysis.

View Article and Find Full Text PDF
Article Synopsis
  • The study focused on analyzing glycemic control and treatment regimens for Type-2 Diabetes Mellitus (T2DM) management in Greece, identifying factors influencing clinical decisions, and measuring compliance with guidelines.
  • Conducted as a national, multicenter registry, it enrolled 1,191 T2DM patients from 59 healthcare sites, stratifying them based on treatment strategies A (lifestyle and one oral agent), B (up to 3 agents excluding insulin), and C (any regimens involving insulin).
  • Results showed that overall, 53% of patients achieved target HbA1c levels, with those on insulin therapy (group C) being older and having poorer compliance compared to other groups, while adherence to guidelines was generally high
View Article and Find Full Text PDF

Background: Enhanced postprandial lipaemia has been reported in patients with obesity, hypertension, metabolic syndrome and type 2 diabetes mellitus (T2DM). We compared 2 oral fat meal tests (LIPOLD: 149g of fat, 56g of carbohydrates and 11.7g of proteins administrated per 2m2 of body surface) and LIPOTEST: 75g of fat, 25g of carbohydrates and 10g of protein with the addition of 15g common sugar) with regard to changes in triglycerides (TGs) as well as other cardiometabolic parameters between baseline and 4 h after the meals.

View Article and Find Full Text PDF