Publications by authors named "S Iliceto"
Article Synopsis
- Prior research was limited in understanding how cardiometabolic risk factors (CVDRFs), like hypertension and diabetes, mediate the link between anxiety/depression and cardiovascular disease (CVD).
- The study followed over 71,000 participants for a decade to assess the impact of anxiety/depression on the development of CVDRFs and the role of neuro-immune mechanisms, with findings showing a clear association and effect differences based on age and sex.
- Results indicated that anxiety/depression significantly increases the risk of developing CVDRFs, especially in younger women, and this relationship may be influenced by neuro-immune pathways.
Article Synopsis
- Autoimmune rheumatic diseases (ARDs) lead to inappropriate immune responses that can significantly increase the risk of cardiovascular issues among patients, affecting their long-term health.
- Endothelial dysfunction and related factors contribute to conditions like atherosclerosis and coronary microvascular dysfunction (CMD), which impairs the heart's ability to respond to increased metabolic demands.
- Advanced imaging techniques, especially stress cardiac magnetic resonance (CMR) and the myocardial perfusion reserve index (MPRI), play a crucial role in detecting CMD in ARDs patients, allowing for early intervention to potentially prevent serious cardiac complications.
Redefining CAV surveillance strategies: Benefits of CCTA vs. ICA.
J Cardiovasc Comput Tomogr
July 2024
Article Synopsis
- - The study investigates the use of cardiac computed tomography angiography (CCTA) as a non-invasive alternative to invasive coronary angiography (ICA) for assessing cardiac allograft vasculopathy (CAV) after heart transplantation.
- - Conducted from March 2021 to February 2023, the research included 260 heart transplant patients, revealing that those undergoing CCTA had significantly lower costs and shorter hospital stays compared to those who underwent ICA.
- - The findings suggest that CCTA is a safer and more cost-effective option for CAV surveillance post-heart transplantation, using less contrast and radiation than ICA.
Background: Age and frailty are associated with underuse of anticoagulation in elderly patients with atrial fibrillation (AF).
Objectives: This study aimed at assessing major clinical outcomes in very elderly patients with AF treated with recommended dose edoxaban and look for a possible relation with frailty measured by a validated score.
Methods: This prospective multicenter cohort study enrolled consecutive very elderly (age ≥80 years) anticoagulation-naïve patients starting recommended doses of edoxaban.