Publications by authors named "S Iismaa"

Aims: Brain fog and fatigue are common issues after acute coronary syndrome. However, little is known about the nature and impact of these experiences in spontaneous coronary artery dissection (SCAD) survivors. The aim of this study was to understand the experiences of brain fog and the coping strategies used after SCAD.

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Article Synopsis
  • This study investigates the prevalence of anxiety and depressive symptoms in survivors of spontaneous coronary artery dissection (SCAD), which is a stressful cause of heart attack.
  • Out of 310 SCAD survivors surveyed, approximately 20% reported anxiety and depressive symptoms, showing these issues persist regardless of the time since the event.
  • Key factors associated with increased risk of anxiety and depression include lack of close social support, financial strain, pre-existing mental health conditions, and younger age.*
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Importance: Spontaneous coronary artery dissection (SCAD) is a poorly understood cause of acute coronary syndrome that predominantly affects women. Evidence to date suggests a complex genetic architecture, while a family history is reported for a minority of cases.

Objective: To determine the contribution of rare and common genetic variants to SCAD risk in familial cases, the latter via the comparison of a polygenic risk score (PRS) with those with sporadic SCAD and healthy controls.

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