Primary hydatid cyst of skeletal muscle: A rare clinical entity.

Introduction: Hydatid cyst is a parasitic infection caused by Echinococcus granulosus, commonly affecting the liver and lungs. Muscular involvement is extremely rare, accounting for only 0.7 % to 0.

Bis-imidazolium ionic liquid and silver nanoparticles mediated synthesis of alginate hydrogels for bacterial skin infection and wound healing applications.

To advance biomedical engineering and enhance its therapeutic and diagnostic capabilities, the development of novel materials that can mimic the complexity of biological tissues is crucial. Hydrogels, with their high water content and biocompatibility, are particularly suitable for a wide range of medical applications. This research explores the synthesis and bioactivity of alginate hydrogels and their crosslinked derivatives within the biomedical field.

The transcriptomic architecture of common cancers reflects synthetic lethal interactions.

To maintain cell fitness, deleterious genetic alterations are buffered by compensatory changes in additional genes. In cancer, buffering processes could be targeted by synthetic lethality. However, despite the large-scale identification of synthetic lethal effects in preclinical models, evidence that these operate clinically is limited.

Exploring pre-exposure prophylaxis (PrEP) modality preferences among black cisgender women attending family planning clinics in Chicago via a cross-sectional mixed-methods study.

Background: Despite pre-exposure prophylaxis (PrEP) demonstrated effectiveness, black cisgender women continue to be at an elevated risk for HIV acquisition and uptake of daily oral PrEP is low in this population in the USA. As advancements in PrEP delivery options continue, it is important to understand women's acceptability of these additional options, specifically black cisgender women, in order to inform uptake and adherence among this population at increased need of HIV prevention options.

Setting: A cross-sectional survey among black cisgender women ages 13-45 (inclusive) attending women's health clinics in Chicago, Illinois, USA, prior to the approval of cabotegravir long-acting injectable.

Exploring the structural and functional dynamics of trimeric and tetrameric states of influenza encoded PB1-F2 viroporin through molecular dynamics simulations.

Influenza Viruses have always been a major health concern due to their highly contagious nature. The PB1-F2 viroporin encoded by the influenza A virus is known to be a pro-apoptotic protein involved in cell death induction of the host immune cells. The structural arrangement and the mode of action of PB1-F2 viroporin have not been fully understood yet.